How a trial works
Most trials happen in four phases. ALSA Research focuses on Phase II, III, and IV studies — meaning safety has typically been established in earlier work, and the goal is to measure how well the treatment works and watch for side effects across larger groups of people.
I
Safety & dosing
II
Effectiveness
III
Confirmation
IV
Post-approval
ALSA runs Phase II–IV studies
Phase I
First in human. A small group of healthy volunteers; the focus is safety and dosing.
Phase II
Tests effectiveness in a larger group of people living with the condition.
Phase III
Confirms effectiveness and monitors side effects, often against standard treatments. Required for FDA approval.
Phase IV
Conducted after approval to study long-term effects across broader populations.
Your protections
Every trial we run is reviewed by an Institutional Review Board — an independent group of physicians, scientists, and community members who confirm the study is ethical and that participants are protected. Participation is always voluntary; you can withdraw at any time without affecting your regular medical care.
What participants get
- Access to potential new treatments before they're widely available
- Close attention from clinical staff during every visit
- Often, study-related care at no cost to you
- Frequently, compensation for time and travel
- The chance to help advance care for others living with the same condition
Ready to take part?
Browse currently enrolling studies at our Manhattan, Bridgeport, or Stamford clinics — or contact us to be notified when a study that matches your situation opens.